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Marx: Oral and Intravenous Bisphosphonate-Induced Osteonecrosis of the Jaws
Marx, Robert E.

Oral and Intravenous Bisphosphonate-Induced Osteonecrosis of the Jaws
History, Etiology, Prevention, and Treatment

2nd Edition 2011
Softcover, 160 Seiten, 211 Abbildungen (farbig)
Sprache: Englisch
Fachgebiete: Fachübergreifend, Implantologie, Oralchirurgie, Zahnheilkunde allgemein

Artikelnr.: 18961
ISBN 978-0-86715-510-5
Quintessence Publishing, USA

 75.00 € 
While many clinicians currently recognize that bisphosphonate usage is associated with osteonecrosis of the jaws, this book establishes the causal relationship between the two, explaining the biologic modes of action that enable bisphosphonates taken both orally and intravenously to induce osteonecrosis of the jaws. Like the first edition, it presents definitive treatment protocols for patients who present at each stage in the progression of osteonecrosis, but this new edition also includes a simplified staging system and information about the serum CTX test for oral bisphosphonate cases. In addition, several management principles and surgical techniques are provided, along with new data on osteopenia and osteoporosis, the conditions for which bisphosphonates are primarily prescribed. The book offers a simple method for predicting risk as well as crucial recommendations for preventing the disease from developing when bisphosphonate therapy is indicated. Comprehensive case histories related to both oral and intravenous bisphosphonates provide direct guidance in managing patients spanning the full presentation spectrum. A must-have for the student and practicing clinician alike.

Chapter 1. Description and History of Bisphosphonate-Induced Osteonecrosis of the Jaws
Chapter 2. Modes of Action and Pharmacokinetics of the Bisphosphonate Family
Chapter 3. Medical Indications for Bisphosphonates
Chapter 4. Osteopetrosis: A Genetic Analogue to Bisphosphonate-Induced Osteonecrosis of the Jaws
Chapter 5. Risks, Prevention, and Management of Intravenous Bisphosphonate-Induced Osteonecrosis of the Jaws
Chapter 6. Risks, Prevention, and Management of Oral Bisphosphonate-Induced Osteonecrosis of the Jaws
Chapter 7. Clinical Pathologic Case Samples
"Anything one could hope to learn about bisphosphonates, from pharmacology to medical indications for their use, is in this text. [...] I would recommend this text as a resource, since every clinician needs to have a solid understanding of bisphosphonates and how to prevent them from causing osteonecrosis of the jaws."
Todd Belfbecker, DMD; Journal of the Massachusetts Dental Society (June 2012)

"All in all, Marx has written an informative and interesting book that is hard to put down. I strongly recommend this book for anyone practicing dentistry who encounters patients on oral or intravenous bisphosphonates in any clinical setting."
R. J. Bate; British Dental Journal (March 2012)